1 | using HeuristicLab.Common;
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2 | using HeuristicLab.Core;
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3 | using HeuristicLab.Encodings.SymbolicExpressionTreeEncoding;
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4 | using HeuristicLab.Persistence.Default.CompositeSerializers.Storable;
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5 | using HeuristicLab.Problems.DataAnalysis.Symbolic;
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6 |
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7 | namespace HeuristicLab.Problems.GeneticProgramming.GlucosePrediction {
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8 | [StorableClass]
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9 | [Item("Blood glucose level forecast grammar", "See MedGEC Workshop at GECCO 2016")]
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10 | public class Grammar : SymbolicExpressionGrammar {
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11 | [StorableConstructor]
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12 | protected Grammar(bool deserializing) : base(deserializing) { }
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13 | protected Grammar(Grammar original, Cloner cloner) : base(original, cloner) { }
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14 |
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15 | public Grammar()
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16 | : base("Blood glucose level forecast grammar", "See MedGEC Workshop at GECCO 2016") {
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17 | Initialize();
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18 | }
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19 |
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20 | public void Initialize() {
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21 | var func = new SimpleSymbol("Func", "The root for the blood glucose forecasting model.", 3, 3);
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22 | var exprGluc = new SimpleSymbol("ExprGluc", string.Empty, 1, 1);
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23 | var exprIns = new SimpleSymbol("ExprIns", string.Empty, 1, 1);
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24 | var exprCh = new SimpleSymbol("ExprCh", string.Empty, 1, 1);
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25 |
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26 | var predGlucData = new PredictedGlucoseVariableSymbol();
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27 | var realGlucData = new RealGlucoseVariableSymbol();
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28 |
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29 | // operators for exprGluc
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30 | var plusGluc = new SimpleSymbol("+", "+", 2, 2);
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31 | var minusGluc = new SimpleSymbol("-", "-", 2, 2);
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32 | var prodGluc = new SimpleSymbol("*", "*", 2, 2);
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33 | var divGluc = new SimpleSymbol("/", "/", 2, 2);
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34 | var expGluc = new SimpleSymbol("Exp", "Exp", 1, 1);
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35 | var sinGluc = new SimpleSymbol("Sin", "Sin", 1, 1);
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36 | var cosGluc = new SimpleSymbol("Cos", "Cos", 1, 1);
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37 | var logGluc = new SimpleSymbol("Log", "Log", 1, 1);
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38 | // var cteGluc = new CteSymbol();
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39 |
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40 | // operators for exprCh
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41 | var plusCh = new SimpleSymbol("+Ch", "+", 2, 2);
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42 | var minusCh = new SimpleSymbol("-Ch", "-", 2, 2);
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43 | var prodCh = new SimpleSymbol("*Ch", "*", 2, 2);
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44 | var divCh = new SimpleSymbol("/Ch", "/", 2, 2);
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45 | var expCh = new SimpleSymbol("ExpCh", "Exp", 1, 1);
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46 | var sinCh = new SimpleSymbol("SinCh", "Sin", 1, 1);
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47 | var cosCh = new SimpleSymbol("CosCh", "Cos", 1, 1);
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48 | var logCh = new SimpleSymbol("LogCh", "Log", 1, 1);
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49 | var curvedCh = new CurvedChVariableSymbol("CurvedCh", "");
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50 | // var cteCh = new CteSymbol();
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51 |
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52 | // operators for exprIns
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53 | var plusIns = new SimpleSymbol("+Ins", "+", 2, 2);
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54 | var minusIns = new SimpleSymbol("-Ins", "-", 2, 2);
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55 | var prodIns = new SimpleSymbol("*Ins", "*", 2, 2);
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56 | var divIns = new SimpleSymbol("/Ins", "/", 2, 2);
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57 | var expIns = new SimpleSymbol("ExpIns", "Exp", 1, 1);
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58 | var sinIns = new SimpleSymbol("SinIns", "Sin", 1, 1);
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59 | var cosIns = new SimpleSymbol("CosIns", "Cos", 1, 1);
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60 | var logIns = new SimpleSymbol("LogIns", "Log", 1, 1);
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61 | var curvedIns = new CurvedInsVariableSymbol("CurvedIns", "");
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62 | var realInsVar = new RealInsulineVariableSymbol();
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63 |
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64 | var constSy = new Constant();
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65 | // var cteCh = new CteSymbol();
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66 |
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67 | AddSymbol(func);
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68 | AddSymbol(exprGluc);
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69 | AddSymbol(exprIns);
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70 | AddSymbol(exprCh);
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71 | AddSymbol(predGlucData);
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72 | AddSymbol(realGlucData);
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73 | AddSymbol(plusGluc);
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74 | AddSymbol(minusGluc);
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75 | AddSymbol(prodGluc);
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76 | AddSymbol(divGluc);
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77 | AddSymbol(expGluc);
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78 | AddSymbol(sinGluc);
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79 | AddSymbol(cosGluc);
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80 | AddSymbol(logGluc);
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81 |
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82 | AddSymbol(curvedCh);
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83 |
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84 | AddSymbol(plusCh);
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85 | AddSymbol(minusCh);
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86 | AddSymbol(prodCh);
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87 | AddSymbol(divCh);
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88 | AddSymbol(expCh);
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89 | AddSymbol(sinCh);
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90 | AddSymbol(cosCh);
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91 | AddSymbol(logCh);
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92 |
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93 | AddSymbol(curvedIns);
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94 | AddSymbol(plusIns);
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95 | AddSymbol(minusIns);
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96 | AddSymbol(prodIns);
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97 | AddSymbol(divIns);
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98 | AddSymbol(expIns);
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99 | AddSymbol(sinIns);
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100 | AddSymbol(cosIns);
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101 | AddSymbol(logIns);
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102 | AddSymbol(realInsVar);
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103 | AddSymbol(constSy);
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104 |
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105 | // <func> ::= <exprgluc> + <exprch> - <exprins>
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106 | AddAllowedChildSymbol(func, exprGluc, 0);
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107 | AddAllowedChildSymbol(func, exprCh, 1);
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108 | AddAllowedChildSymbol(func, exprIns, 2);
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109 |
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110 | /* # Glucose |
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111 | <exprgluc> ::= (<exprgluc> <op> <exprgluc>) |
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112 | |<preop> (<exprgluc>) |
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113 | |(<cte> <op> <exprgluc>) |
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114 | |predictedData(k-<idxCurr2h>) |
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115 | |realData(k-<idx2hOrMore>)
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116 | */
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117 | var opGlucSet = new Symbol[] { plusGluc, minusGluc, prodGluc, divGluc, expGluc, sinGluc, cosGluc, logGluc, predGlucData, realGlucData, constSy };
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118 | foreach (var opGluc in opGlucSet) {
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119 | AddAllowedChildSymbol(exprGluc, opGluc);
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120 | }
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121 |
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122 |
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123 | foreach (var parentOp in new Symbol[] { plusGluc, minusGluc, prodGluc, divGluc }) {
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124 | foreach (var childOp in opGlucSet) {
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125 | AddAllowedChildSymbol(parentOp, childOp, 0);
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126 | AddAllowedChildSymbol(parentOp, childOp, 1);
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127 | }
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128 | }
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129 | // <exprgluc> ::= <preop> (<exprgluc>)
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130 | foreach (var parentOp in new Symbol[] { expGluc, sinGluc, cosGluc, logGluc }) {
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131 | foreach (var childOp in opGlucSet) {
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132 | AddAllowedChildSymbol(parentOp, childOp, 0);
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133 | }
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134 | }
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135 |
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136 | /*
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137 | # CH |
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138 | <exprch> ::= (<exprch> <op> <exprch>) |
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139 | |<preop> (<exprch>) |
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140 | |(<cte> <op> <exprch>) |
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141 | |(getPrevData(1,k,1) * <cte> * <curvedCH>) |
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142 | |
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143 | # CH in 2 (0.041,24), 3 (0.027,36) and 4 (0.02,48) hours with 3 shapes of beta: |
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144 | <curvedCH> ::= beta(0.041*Math.min(24,getPrevDataDistance(1,k,1)),2,5) |
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145 | |beta(0.041*Math.min(24,getPrevDataDistance(1,k,1)),3,3) |
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146 | |beta(0.041*Math.min(24,getPrevDataDistance(1,k,1)),5,2) |
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147 | |beta(0.027*Math.min(36,getPrevDataDistance(1,k,1)),2,5) |
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148 | |beta(0.027*Math.min(36,getPrevDataDistance(1,k,1)),3,3) |
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149 | |beta(0.027*Math.min(36,getPrevDataDistance(1,k,1)),5,2) |
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150 | |beta(0.02*Math.min(48,getPrevDataDistance(1,k,1)),2,5) |
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151 | |beta(0.02*Math.min(48,getPrevDataDistance(1,k,1)),3,3) |
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152 | |beta(0.02*Math.min(48,getPrevDataDistance(1,k,1)),5,2)
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153 | */
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154 | var opChSet = new Symbol[] { plusCh, minusCh, prodCh, divCh, expCh, sinCh, cosCh, logCh, curvedCh, constSy };
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155 | foreach (var opCh in opChSet) {
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156 | AddAllowedChildSymbol(exprCh, opCh);
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157 | }
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158 |
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159 | foreach (var parentOp in new Symbol[] { plusCh, minusCh, prodCh, divCh }) {
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160 | foreach (var childOp in opChSet) {
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161 | AddAllowedChildSymbol(parentOp, childOp, 0);
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162 | AddAllowedChildSymbol(parentOp, childOp, 1);
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163 | }
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164 | }
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165 | // <exprch> ::= <preop> (<exprch>)
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166 | foreach (var parentOp in new Symbol[] { expCh, sinCh, cosCh, logCh }) {
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167 | foreach (var childOp in opChSet) {
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168 | AddAllowedChildSymbol(parentOp, childOp, 0);
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169 | }
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170 | }
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171 |
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172 | /*
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173 | # Insulin: |
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174 | ## Sum of insulins in past 2h minus the peak |
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175 | ## Curve for the peak in past 2h |
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176 | <exprins> ::= (<exprins> <op> <exprins>) |
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177 | |<preop> (<exprins>) |
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178 | |(<cte> <op> <exprins>) |
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179 | |getVariable(2,k-<idx>) |
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180 | |(getSumOfValues(24,k,2) - getMaxValue(24,k,2) <op> (getMaxValue(24,k,2) <op> <curvedINS>)) |
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181 | |
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182 | # INS in 2 (0.041,24), 3 (0.027,36) and 4 (0.02,48) hours with 3 shapes of beta: |
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183 | <curvedINS> ::= beta(0.041*Math.min(24,getMaxValueDistance(24,k,2)),2,5) |
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184 | |beta(0.041*Math.min(24,getMaxValueDistance(24,k,2)),3,3) |
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185 | |beta(0.041*Math.min(24,getMaxValueDistance(24,k,2)),5,2) |
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186 | |beta(0.027*Math.min(36,getMaxValueDistance(36,k,2)),2,5) |
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187 | |beta(0.027*Math.min(36,getMaxValueDistance(36,k,2)),3,3) |
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188 | |beta(0.027*Math.min(36,getMaxValueDistance(36,k,2)),5,2) |
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189 | |beta(0.02*Math.min(48,getMaxValueDistance(48,k,2)),2,5) |
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190 | |beta(0.02*Math.min(48,getMaxValueDistance(48,k,2)),3,3) |
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191 | |beta(0.02*Math.min(48,getMaxValueDistance(48,k,2)),5,2) |
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192 |
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193 | */
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194 | var opInsSet = new Symbol[] { plusIns, minusIns, prodIns, divIns, expIns, sinIns, cosIns, logIns, realInsVar, curvedIns, constSy };
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195 | foreach (var opIns in opInsSet) {
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196 | AddAllowedChildSymbol(exprIns, opIns);
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197 | }
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198 |
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199 | // <exprins> ::= (<exprins> <op> <exprins>)
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200 | // <exprins> ::= (<cte> <op> <exprins>)
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201 | foreach (var parentOp in new Symbol[] { plusIns, minusIns, prodIns, divIns }) {
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202 | foreach (var childOp in opInsSet) {
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203 | AddAllowedChildSymbol(parentOp, childOp, 0);
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204 | AddAllowedChildSymbol(parentOp, childOp, 1);
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205 | }
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206 | }
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207 | // <exprins> ::= <preop> (<exprins>)
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208 | foreach (var op in new Symbol[] { expIns, sinIns, cosIns, logIns }) {
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209 | foreach (var childOp in opInsSet) {
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210 | AddAllowedChildSymbol(op, childOp, 0);
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211 | }
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212 | }
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213 |
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214 | // root is func
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215 | AddAllowedChildSymbol(StartSymbol, func);
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216 | }
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217 |
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218 | public override IDeepCloneable Clone(Cloner cloner) {
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219 | return new Grammar(this, cloner);
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220 | }
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221 | }
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222 | }
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